ea0012p98 | Reproduction | SFE2006
Hodges LM
, Chin EC
, Nadaffy JM
, Brickell J
, Cheng Z
, Sheldrick EL
, Flint APF
, Wathes DC
, Abayasekara DRE
Public health policy in recent years has favoured a reduction in saturated fats in favour of polyunsaturated fats due to the numerous health benefits of polyunsaturated fatty acids (PUFAs). Previous studies have demonstrated that PUFAs modulate gonadal steroidogenesis. We have therefore investigated the hypothesis that PUFAs modify steroidogenesis through affecting components of the cholesterol metabolising machinery, including steroidogenic acute regulatory (StAR) protein and...